Synthesis and in vitro microbiological evaluation of an array of biolabile 2-morpholino-N-(4, 6-diarylpyrimidin-2-yl) acetamides

…, J Thanusu, M Gopalakrishnan

文献索引：Kanagarajan; Thanusu; Gopalakrishnan European Journal of Medicinal Chemistry, 2010 , vol. 45, # 4 p. 1583 - 1589

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被引用次数: 34

摘要

Biolabile 2-morpholino-N-(4, 6-diarylpyrimidin-2-yl) acetamides 34–42 have been synthesized and evaluated for their in vitro antibacterial and antifungal activities. The minimum inhibitory concentration tested for the same compounds against the same set of bacterial and fungal strains shows that the compounds 36 and 38 against β-Heamolytic streptococcus and Klebsiella pneumonia, 40 against Escherichia coli and Pseudomonas, ...