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Preparation of N 2-protected amino acid aldehydes via reduction of corresponding acid halides with lithium tris-(tert. butoxy)-aluminium hydride

P Zlatoidsky

文献索引:Zlatoidsky, Pavol Tetrahedron Letters, 1995 , vol. 36, # 40 p. 7281 - 7284

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被引用次数: 14

摘要

N-protected amino aldehydes are important intermediates m the synthesis of many types of proteinase inhibitors containing transition state analogues or peptide bond isosters z . Several methods for preparation of these compounds were reported 2-8 In this contribution, we wish to report the