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Process research and scale-up of a commercialisable route to maraviroc (UK-427,857), a CCR-5 receptor antagonist

J Åhman, M Birch…

文献索引:Soai; Oyamada; Takase Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 8 p. 2327 - 2328

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被引用次数: 23

摘要

... 1113. DOI: 10.1021/op800062d. Publication Date (Web): October 4, 2008. Copyright © 2008 American Chemical Society. ... figure Scheme 3. Chemical research and development a. ... The process safety evaluation of this chemistry determined the maximum rate of hydrogen evolution ...