Tetrahedron

Palladium-catalyzed C–N bond formation: Synthesis of 1-aryl-1H-pyrazoles from β-bromovinyl aldehydes and arylhydrazines

CS Cho, DB Patel

文献索引：Cho, Chan Sik; Patel, Daksha B. Tetrahedron, 2006 , vol. 62, # 26 p. 6388 - 6391

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被引用次数: 47

摘要

Cyclic and acyclic β-bromovinyl aldehydes are cyclized with an array of arylhydrazines in toluene at 125 °C in the presence of a palladium catalyst and a phosphorus chelating ligand together with NaO t Bu to give 1-aryl-1H-pyrazoles in moderate to good yields. ... Based on our recent