1, 5-Diphenyl-1, 4-pentadiene-3-ones and cyclic analogues as antioxidative agents. Synthesis and structure-activity relationship

…, MS Reksohadiprodjo, L Hakim, H Van der Goot…

文献索引：Sardjiman; Reksohadiprodjo; Hakim; Van Der Goot; Timmerman European Journal of Medicinal Chemistry, 1997 , vol. 32, # 7-8 p. 625 - 630

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被引用次数: 88

摘要

A series of 1, 5-diphenyl-1, 4-pentadiene-3-ones and cyclic analogues with OH-groups in the para position of the phenyl rings and various meta substituents were prepared and their antioxidant activity compared with that of curcumin. Most of them exhibited potent antioxidative activity, especially when all the meta positions were substituted by methoxy groups.