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Preparation and anti-inflammatory activities of diarylheptanoid and diarylheptylamine analogs

…, WJ Huang, WW Lin, SS Lee, CH Chen

文献索引:Lee, Su-Lin; Huang, Wei-Jan; Lin, Wan Wan; Lee, Shoei-Sheng; Chen, Chung-Hsiung Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 22 p. 6175 - 6181

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被引用次数: 69

摘要

Seven diarylheptylamine (12a–g) and four diarylheptanoid analogs (3–5, 9), structurally related to the natural anti-inflammatory agent oregonin (1), have been prepared from curcumin (2) for evaluation of their activity against the expression of iNOS and COX-2. ...