Organic letters

Biaryl Synthesis via Decarboxylative Pd-Catalyzed Reactions of Arenecarboxylic Acids and Diaryliodonium Triflates

JM Becht, CL Drian

文献索引：Becht, Jean-Michel; Le Drian, Claude Organic Letters, 2008 , vol. 10, # 14 p. 3161 - 3164

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被引用次数: 125

摘要

A novel simple and efficient synthesis of biaryls via a Pd-catalyzed decarboxylative cross- coupling reaction of arenecarboxylic acids and diaryliodonium triflates is described. The PdCl2/DPEphos catalytic system in the presence of Ag2CO3 in DMSO was found to be the most efficient. Various biaryls, including sterically hindered biaryls, were synthesized with yields ranging from 37 to 85%.