Tetrahedron: Asymmetry

(S)-Serine derived N–O and N–P oxazoline ligands for asymmetric catalysis

G Jones, CJ Richards

文献索引：Jones, Geraint; Richards, Christopher J. Tetrahedron Asymmetry, 2004 , vol. 15, # 4 p. 653 - 664

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被引用次数: 37

摘要

(S)-Serine methyl ester and a range of carboxylic acids RCO2H (R=(η5-C5H4) Fe (η5- C5Ph5),(η5-C5H4) Co (η4-C4Ph4),(η5-C5H4) Fe (η5-C5H5), 1-adamantyl, C6H5) were readily transformed in three steps into (R)-4-hydroxymethyloxazoline N–O ligands containing the R substituent at position 2. Two further N–O ligands (S)-4-(1-hydroxy-1- methylethyl) oxazoline and (S)-4-(1-hydroxy-1, 1-diphenylmethyl) oxazoline both ...