Synthesis

A Facile Synthesis of Oxazolines, Thiazolines, and Imidazolines Using α, α-Difluoroalkylamines

T Fukuhara, C Hasegawa, S Hara

文献索引：Fukuhara, Tsuyoshi; Hasegawa, Chihiro; Hara, Shoji Synthesis, 2007 , # 10 p. 1528 - 1534

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被引用次数: 17

摘要

Abstract β-Amino alcohols, β-amino thiols, and β-diamines can be converted to the corresponding oxazoline, thiazoline, and imidazoline derivatives, respectively, by reaction with α, α-difluoroalkylamines under mild conditions. The reaction is applicable for the synthesis of optically active heterocyclic compounds.