Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities

H Tang, Y Yan, Z Feng, RK de Jesus, L Yang…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 20 p. 6088 - 6092

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被引用次数: 14

摘要

... Bioorganic & Medicinal Chemistry Letters. ... The structures of the two most potent hits are shown in Figure 2. In this communication, we will outline the medicinal chemistry efforts leading to the discovery of a novel class of MCD inhibitors containing the 1,1,1,3,3,3-hexafluoro ...