Asymmetric Synthesis of Monofluorinated 1-Amino-1, 2-dihydronaphthalene and 1, 3-Amino Alcohol Derivatives

…, R Román, DM Sedgwick, G Haufe, P Barrio…

文献索引：Luebke, Martin; Jung, Manfred; Haufe, Guenter Journal of Fluorine Chemistry, 2013 , vol. 152, p. 144 - 156

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被引用次数: 6

摘要

Enantioenriched 1-amino-4-fluoro-1, 2-dihydronaphthalene derivatives are accessed via two complementary synthetic strategies. The careful optimization of the reaction conditions required for the elimination step in one route has allowed both the identification of an