Discovery of a novel route to β-thymidine: a precursor for anti-AIDS compounds

AV RamaáRao, VS Sista

文献索引：Rao, A. V. Rama; Gurjar, Mukund K.; Lalitha, Sista V. S. Journal of the Chemical Society, Chemical Communications, 1994 , # 10 p. 1255 - 1256

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被引用次数: 12

摘要

11 cesses are reported for P-thymidine. However, these processes are fraught with difficulties such as the formation of a-and P-anomers with 2-deoxy-~-ribose as a starting material. Although, with D-ribose, the problem of a-and P-anomers was circumvented, the high cost of D-ribose poses limitations. 2 During our studies on 2', 3'-dideoxynucleosides, 4 we discovered5 a novel rearrangement by serendipity leading to the formation of P- ...