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Reductive removal of methoxyacetyl protective group using sodium borohydride

…, F Corbo, R Sharma, S Sarveswari, A Roychowdhury

文献索引:Gadekar, Pradip K.; Hoermann, Maryann; Corbo, Faith; Sharma, Rajiv; Sarveswari; Roychowdhury, Abhijit Tetrahedron Letters, 2014 , vol. 55, # 2 p. 503 - 506

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被引用次数: 0

摘要

Abstract Herein, we have developed a mild and selective reductive deprotection method for the MAc protected alcohols using sodium borohydride. The new deprotection conditions provide a complete orthogonality between O-MAc and other protecting groups such as tert- butyl ester, N-Boc, Fmoc, Cbz, O-TBDMS, N-benzyl, O-benzyl, O-acetyl, N-acetyl, N-MAc, etc. In addition to O-MAc deprotection, this method is also applicable for S-MAc ...