Molecules

A straightforward diphenylmethyl Protection method and deprotection of some pyrimidine nucleosides

M Saudi, A Van Aerschot

文献索引：Saudi, Milind; Van Aerschot, Arthur Molecules, 2013 , vol. 18, # 7 p. 8524 - 8534

全文：HTML全文

被引用次数: 4

摘要

Abstract: Benzhydryl protection of primary and secondary alcohols has been reported previously via reaction with metal alcoholates. Our aim was to find generally useful and very mild conditions for the alcoholic protection and deprotection of nucleosides with the diphenylmethyl group. This was accomplished for some pyrimidine nucleosides using PdCl 2 as the transition metal catalyst, and with optimization yields of 70–90% have been ...