Strategy for 14C??labeling of a series of bis (heteroaryl) piperazines

OK Arjomandi, N Saemian, G Shirvani…

文献索引：Arjomandi, Omid Khalili; Saemian, Nader; Shirvani, Gholamhossein; Javaheri, Mohsen; Esmailli, Kameh Journal of Labelled Compounds and Radiopharmaceuticals, 2011 , vol. 54, # 7 p. 363 - 366

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被引用次数: 10

摘要

Abstract Four bis (heteroaryl) piperazines labeled with carbon-14 in the 2-position of imidazole moiety were prepared as part of a 4-step (or 5-step) sequence from 5- hydroxymethyl-2-mercapto-1-benzylimida-zole-[2-14 C] as a key synthetic intermediate which has been synthesized from potassium [14 C]-thiocyanate. Copyright© 2011 John Wiley & Sons, Ltd.