Synthesis of Novel Galactopyranosyl??Derived Spiro Barbiturates

VN Ingle, PK Gaidhane, SS Dutta…

文献索引：Ingle; Gaidhane; Dutta; Naha; Sengupta Journal of Carbohydrate Chemistry, 2006 , vol. 25, # 8-9 p. 661 - 671

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被引用次数: 3

摘要

Abstract Malonic acid undergoes condensation readily with ureas to yield barbituric acids 2, which on bromination give 5, 5??dibromobarbituric acids 3. Reaction of α??d??galactose with these 5, 5??dibromo barbituric acids afforded 2, 3?螃窿?d??galactopyrano??1, 4??dioxo??7, 9??diaza?? spiro [4, 5] deca??6, 8, 10??triones 4. The structures of the products have been assigned on the basis of 1H NMR, 13C NMR, FAB??MS, optical activity, and elemental analysis. The title ...