Tetrahedron Letters

Preparation of 5-formyl-and 5-acetylbarbituric acids, including the corresponding Schiff bases and phenylhydrazones

BS Jursic, DM Neumann

文献索引：Jursic, Branko S; Neumann, Donna M Tetrahedron Letters, 2001 , vol. 42, # 48 p. 8435 - 8439

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被引用次数: 43

摘要

Simple, effective, and high yield synthetic procedures for formylation and acetylation of barbituric acid derivatives is described. Generated 5-acylbarbituric acids are transformed into the corresponding Schiff bases in high yield condensation reactions with ω- aminoalkanoic acids and nitrophenylhydrazines.