Tetrahedron letters

A new generation of “instant ylids”: Powder mixtures of phosphonium salts and potassium hydride as storable precursors to Wittig reagents

M El-Khoury, Q Wang, M Schlosser

文献索引：El-Khoury, Mirella; Wang, Qian; Schlosser, Manfred Tetrahedron Letters, 1996 , vol. 37, # 50 p. 9047 - 9048

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被引用次数: 9

摘要

Mixing a finely pulverized alkyltriphenylphosphonium salt and potassium hydride in 1: 1 molar ratio gives a ready-to-use powder the components of which react rapidly when tert- butyl methyl ether is added under stirring. When, in general after a few minutes, the generation of the (triphenyl-phosphonio) alkanide is complete, it can be immediately used for the Wittig olefination of a carbonyl compound. Compared to sodium amide based “ ...