Tetrahedron

Synthesis and microbial transformation of β-amino nitriles

…, L Martínková, AC Knall, S Krahulec, N Klempier

文献索引：Winkler, Margit; Martinkova, Ludmila; Knall, Astrid C.; Krahulec, Stefan; Klempier, Norbert Tetrahedron, 2005 , vol. 61, # 17 p. 4249 - 4260

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被引用次数: 52

摘要

Rhodococcus equi A4, Rhodococcus erythropolis NCIMB 11540 and Rhodococcus sp. R312 were investigated towards their ability to produce β-amino amides and acids from β- amino nitriles. The microorganisms show comparable trends: five-membered alicyclic 2- amino nitriles were transformed significantly faster than the six-membered compounds and the products of trans-2-amino nitriles (amides and acids) were formed considerably faster ...