A facile preparation of various N-heterocycles using amides and olefins

…, TJ Meyerhoefer, S Kershaw, V Huang, M De Castro

文献索引：Gratia, Synthia S.; Vigneau, Edward S.; Eltayeb, Sumiea; Patel, Kishan; Meyerhoefer, Terence J.; Kershaw, Sonia; Huang, Victor; De Castro, Michael Tetrahedron Letters, 2014 , vol. 55, # 2 p. 448 - 452

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被引用次数: 2

摘要

Abstract We herein report a one pot approach for the synthesis of various nitrogen containing heterocycles including: oxazolines, thiazolines, and dihydro dioxazines via the addition of amides to olefins in the presence of N-iodosuccinimide (NIS) and propionitrile at high temperatures. Thus, the reaction of aryl/heteroaryl amides, thioamides, N- hydroxybenzamide, and phenylurea with various olefins in the presence of NIS and ...