Chemistry Letters

A convenient trifluoroacetylation of arenes with 2-(trifluoroacetoxy) pyridine.

T Keumi, M Shimada, M Takahashi, H Kitajima

文献索引：Keumi, Takashi; Shimada, Masakazu; Takahashi, Masahiro; Kitajima, Hidehiko Chemistry Letters, 1990 , # 5 p. 783 - 786

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被引用次数: 15

摘要

2-(Trifluoroacetoxy) pyridine (TFAP) is useful for trifluoroacetylating arenes under the Friedel– Crafts conditions. Benzene, alkylbenzenes, naphthalene, and dibenzofuran have reacted with TFAP in the presence of aluminum chloride in dichloromethane to give the corresponding trifluoromethyl aryl ketones in good isolated yields.