Chemistry Letters

A convenient trifluoroacetylation of arenes with 2-(trifluoroacetoxy) pyridine.

T Keumi, M Shimada, M Takahashi, H Kitajima

Index: Keumi, Takashi; Shimada, Masakazu; Takahashi, Masahiro; Kitajima, Hidehiko Chemistry Letters, 1990 , # 5 p. 783 - 786

Full Text: HTML

Citation Number: 15

Abstract

2-(Trifluoroacetoxy) pyridine (TFAP) is useful for trifluoroacetylating arenes under the Friedel– Crafts conditions. Benzene, alkylbenzenes, naphthalene, and dibenzofuran have reacted with TFAP in the presence of aluminum chloride in dichloromethane to give the corresponding trifluoromethyl aryl ketones in good isolated yields.