Functionalized arylzinc compounds in ethereal solvent: Direct synthesis from aryl iodides and zinc powder and application to Pd-catalyzed reaction with allylic halides

R Ikegami, A Koresawa, T Shibata…

文献索引：Ikegami, Ryo; Koresawa, Akiko; Shibata, Takanori; Takagi, Kentaro Journal of Organic Chemistry, 2003 , vol. 68, # 6 p. 2195 - 2199

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被引用次数: 46

摘要

Arylzinc compounds, ArZnX, were conveniently prepared in high yields by the reaction of zinc powder with aryl iodides, which contain electron-withdrawing groups such as CO2CH3, CN, Br, or CF3 at the ortho-, meta-or para-position, or electron-donating groups such as CH3, OCH3, or H, at 70° C in THF, at 100° C, or at 130° C in diglyme, respectively. Pd (dba) 2 exhibited an outstanding efficient catalytic effect for the cross-coupling of these ethereal ...