Journal of the American Chemical Society

Intramolecular hydroamination of unbiased and functionalized primary aminoalkenes catalyzed by a rhodium aminophosphine complex

LD Julian, JF Hartwig

文献索引：Julian, Lisa D.; Hartwig, John F. Journal of the American Chemical Society, 2010 , vol. 132, # 39 p. 13813 - 13822

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被引用次数: 94

摘要

We report a rhodium catalyst that exhibits high reactivity for the hydroamination of primary aminoalkenes that are unbiased toward cyclization and that possess functional groups incompatible with more electrophilic hydroamination catalysts. The rhodium catalyst contains an unusual diaminophosphine ligand (L1) that binds to rhodium in a κ3-P, O, P mode. The reactions catalyzed by this complex typically proceed at mild temperatures ( ...