Tetrahedron

Synthesis of N-substituted aziridine-2-carboxylates

Z Bernstein, D Ben-Ishai

文献索引：Bernstein,Z.; Ben-Ishai,D. Tetrahedron, 1977 , vol. 33, p. 881 - 883

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被引用次数: 65

摘要

The synthesis of the methyl esters of N-methoxycarbonyl-and N-benzyloxycarbonylaziridine- 2-carboxylic acid 2 by reacting methyl 2-chloro-N-carbalkoxyglycinate 1 with diazomethane is described. The aziridines were readily converted to derivatives of O-methylserine 5 and S- methylcysteine 6.