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Synthesis of a series of compounds related to betaxolol, a new. beta. 1-adrenoceptor antagonist with a pharmacological and pharmacokinetic profile optimized for the …

PM Manoury, JL Binet, J Rousseau…

文献索引:Journal of Medicinal Chemistry, , vol. 30, # 6 p. 1003 - 1011

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被引用次数: 65

摘要

... are drugs that have variable degrees of potency associated with ancillary properties such as membrane stabilizing activity, relative selectivity toward the &-adrenoceptor 0 1987 American Chemical Society Page 2. 1004 Journal of Medicinal Chemistry, 1987, Vol. ...