Synthesis and anticancer and anti-HIV testing of some pyrazino [1, 2-a] benzimidazole derivatives

Ş Demirayak, UA Mohsen, AÇ Karaburun

文献索引：Demirayak, Seref; Abu Mohsen, Usama; Cagri Karaburun, Ahmet European Journal of Medicinal Chemistry, 2002 , vol. 37, # 3 p. 255 - 260

全文：HTML全文

被引用次数: 128

摘要

In this study, some 1-methylene-2, 3-diaryl-1, 2-dihydropyrazino [1, 2-a] benzimidazole and some 1-(2-arylvinyl)-3-arylpyrazino [1, 2-a] benzimidazole derivatives were synthesised. The structure elucidation of the compounds was performed by IR, 1H-NMR and MASS spectroscopic data and elemental analyses results. Anticancer and anti-HIV activities of the compounds were examined, however no anti-HIV activity was seen; highly notable ...