Organic letters

Rhenium-catalyzed aromatic propargylation

JJ Kennedy-Smith, LA Young, FD Toste

文献索引：Kennedy-Smith, Joshua J.; Young, Lauren A.; Toste, F. Dean Organic Letters, 2004 , vol. 6, # 8 p. 1325 - 1327

全文：HTML全文

被引用次数: 135

摘要

A mild aromatic propargylation reaction, employing an air-and moisture-tolerant rhenium- oxo complex ((dppm) ReOCl3) as a catalyst and a propargyl alcohol as the electrophile, is described. The reaction tolerates a broad range of functional groups and regioselectively affords propargylic arenas without formation of the isomeric allenyl adducts. The potential of this rhenium (V)-catalyzed reaction is exemplified by application of the propargylation to ...