Tetrahedron letters

The palladium catalyzed allylic alkylation of bis (trimethylsilyl) substituted propenyl acetates or carbonates in the presence of chiral ligands

DL Romero, EL Fritzen

文献索引：Romero, Donna L.; Fritzen, Edward L. Tetrahedron Letters, 1997 , vol. 38, # 50 p. 8659 - 8662

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被引用次数: 15

摘要

Palladium catalyzed asymmetric allylic alkylations of a bis (trimethylsilyl) substituted propenyl acetate and carbonate were investigated using various chiral ligands and reaction conditions. The best enantioselectivity (86% ee) was obtained with the substrate 1-phenyl-3, 3-bis (trimethylsilyl) propenyl carbonate 13 and the chiral oxazoline ligand 4c.