Mesitylmagnesium Bromide as a Reagent in the Acetoacetic Ester Condensation1

MA Spielman, MT Schmidt

文献索引：Spielman; Schmidt Journal of the American Chemical Society, 1937 , vol. 59, p. 2010

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被引用次数: 7

摘要

An investigation recently completed in this Laboratory2 has revealed that neither ethyl isovalerate nor ethyl t-butylacetate undergoes the acetoacetic ester condensation in the presence of sodium ethoxide, either under equilibrium conditions or when provision is made for removal of alcohol from the reaction mixture. Both of these esters contain an a-methylene group, but their non-reactivity places them in a category with ethyl isobutyrate, which is ...