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Highly enantioselective separation using a supported liquid membrane encapsulating surfactant-enzyme complex

E Miyako, T Maruyama, N Kamiya…

文献索引:Miyako, Eijiro; Maruyama, Tatsuo; Kamiya, Noriho; Goto, Masahiro Journal of the American Chemical Society, 2004 , vol. 126, # 28 p. 8622 - 8623

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被引用次数: 45

摘要

We developed a highly enantioselective separation system for the optically active compounds,(S)-ibuprofen and l-phenylalanine, from their racemic mixtures by employing a supported liquid membrane (SLM) encapsulating a surfactant-lipase complex (or a surfactant-α-chymotrypsin complex). In the present system, enzymes encapsulated in the liquid-membrane phase effectively drove the enantioselective transport of optically active ...