Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Stereochemical control in microbial reduction 4. Effect of cultivation conditions on the reduction of β-keto esters by methylotrophic yeasts. ... When β-keto esters are reduced by methanol grown yeast, drastic shift of the enantiomer excess of the products toward D-isomer formation is ...