2-Aminopyridine derivatives, though well known for a long time, have attracted considerable interest recently because of their applications in various fields especially in pharmaceutical research. For example, the use of 2-aminopyridines have been reported as glucokinase activators 1 or selective inhibitors of neuronal nitric oxide synthase. 2 Substituted or unsubstituted aminopyridines are also useful precursors for the synthesis of a variety of heteocyclic compounds ...
