The N-alkylation of primary amines to secondary amines is of fundamental importance in organic synthesis, granting access to valuable N-alkylamines that are widely used as pharmacophores in numerous biologically active compounds, dyes, agrochemicals and functionalized materials.[1] The most commonly used method for N-alkylation is the coupling of amines with alkyl halides [2] in the presence of stoichiometric amounts of bases. This ...
