Synthetic communications

An improved synthesis of (E)-cinnamic acid derivatives via the Claisen–Schmidt condensation

M Hatsuda, T Kuroda, M Seki

文献索引：Hatsuda, Masanori; Kuroda, Tooru; Seki, Masahiko Synthetic Communications, 2003 , vol. 33, # 3 p. 427 - 434

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被引用次数: 25

摘要

A variety of (E)-cinnamic acid derivatives are prepared in high yields through the Claisen–Schmidt condensation in the presence of sodium metal and a catalytic amount of methanol with toluene employed as the co-solvent. ... A variety of (E)-cinnamic acid derivatives are prepared in high yields through the Claisen–Schmidt condensation in the presence of sodium metal and a catalytic amount of methanol with toluene employed as the co-solvent.