Bismuth nitrate promoted Fischer indole synthesis: A simple and convenient approach for the synthesis of alkyl indoles

A Sudhakara, H Jayadevappa…

文献索引：Sudhakara, Aralihalli; Jayadevappa, Honnali; Kumar, Hosanagara N.H.; Mahadevan, Kittappa M. Letters in Organic Chemistry, 2009 , vol. 6, # 2 p. 159 - 164

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被引用次数: 14

摘要

A novel one-pot fisher indole synthesis approach has been developed by using bismuth nitrate as a catalyst. Yields around 90-95% were obtained after reaction in methanol at reflux temperature in 20-40 min. Apart from the mild reaction conditions of the process and its excellent results, the simplicity of product isolation and the possibility to recycle the bismuth nitrate offers a significant advantage.