Tetrahedron Letters

A one-pot, two-step microwave-assisted synthesis of highly functionalized benzoxazoles using solid-supported reagents (SSRs)

M Radi, S Saletti, M Botta

文献索引：Radi, Marco; Saletti, Sara; Botta, Maurizio Tetrahedron Letters, 2008 , vol. 49, # 29-30 p. 4464 - 4466

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被引用次数: 24

摘要

A one-pot, two-step protocol for the microwave-assisted solid-phase synthesis of substituted benzoxazoles has been developed starting from different polymer-bound esters we previously designed as solid-supported reagents (SSRs) for the acylation of amines, alcohols and phenols. The combination of a parallel synthesizer and a microwave reactor allowed to quickly prepare a collection of substituted benzoxaxoles in high purity and ...