Synthetic Communications®

Sodium Borohydride–Mediated Transesterification

G Sereda, S Pothula, J Dreessen

文献索引：Sereda, Grigoriy; Pothula, Swetha; Dreessen, James Synthetic Communications, 2010 , vol. 40, # 9 p. 1312 - 1321

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被引用次数: 4

摘要

In the presence of sodium borohydride, esters react with alcohols with formation of the corresponding esters. The reaction is sensitive to the solvent, structure of the ester, and is often concurrent with reduction. Thioesters containing an ester group can be selectively cleaved by the reagent. Both esters and thioesters attached to solid support are resistant toward sodium borohydride. The in situ prepared sodium tetraalkoxyborate is introduced ...