Synthesis of eight stereoisomers of pochonicine: nanomolar inhibition of β-N-acetylhexosaminidases

JS Zhu, S Nakagawa, W Chen, I Adachi…

文献索引：Hernandez, J. Nicolas; Crisostomo, Fernando R. Pinacho; Martin, Tomas; Martin, Victor S. European Journal of Organic Chemistry, 2007 , # 30 p. 5050 - 5058

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被引用次数: 26

摘要

... J. Org. ... Finally, the second pyrrolidine ring could be assembled through dihydroxylation of the allyl group followed by intramolecular S N 2 ... After oxidation of the unmasked primary hydroxyl group in 13L with Dess–Martin periodinane (DMP), the resulting aldehyde 14L was ...