Convenient Synthesis of Structurally Novel 1, 3??Disubstituted Azetidine Derivatives

RK Kharul, A Goswami, A Gite, AK Godha…

文献索引：Kharul, Rajendra K.; Goswami, Amitgiri; Gite, Archana; Godha, Atul K.; Jain, Mukul; Patel, Pankaj R. Synthetic Communications, 2008 , vol. 38, # 11 p. 1703 - 1717

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被引用次数: 4

摘要

Abstract A convenient synthesis of structurally novel 1, 3??disubstituted azetidine derivatives is described. The approach involves condensation of an azetidine building block with sulfonylated carbamic acid methyl ester, subsequently followed by quenching the imidoyl chloride with amines. Different derivatives were prepared by substituting benzhydrol as well as benzenesulfonamide as part of the core structure.