Tetrahedron

Direct construction of quaternary carbons from carbonyl compounds utilizing low-valent vanadium complexes

Y Kataoka, I Makihira, H Akiyama, K Tani

文献索引：Kataoka, Yasutaka; Makihira, Isamu; Akiyama, Hiroaki; Tani, Kazuhide Tetrahedron, 1997 , vol. 53, # 28 p. 9525 - 9540

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被引用次数: 16

摘要

Direct geminal diallylation of a carbonyl compound with allyl bromide has been achieved in the presence of a low-valent vanadium complex and zinc. The diallylation has been found to proceed stepwise and the two allyl groups were introduced successively. By applying this method, one-pot synthesis of asymmetric quaternary carbons has been accomplished. As the first alkylating reagent a combination of allyl bromide and zinc, a Grignard reagent, or ...