Journal of Molecular Catalysis A: Chemical

Facile synthesis of dihydrochalcones via the AlCl 3-promoted tandem Friedel–Crafts acylation and alkylation of arenes with 2-alkenoyl chlorides

Y Zhou, X Li, S Hou, J Xu

文献索引：Zhou, Yang; Li, Xinyao; Hou, Shili; Xu, Jiaxi Journal of Molecular Catalysis A: Chemical, 2012 , vol. 365, p. 203 - 211

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被引用次数: 13

摘要

Tandem Friedel–Crafts acylation and alkylation of arenes with 2-alkenoyl chlorides were investigated under the catalysis of Lewis acids. The cascade reaction affords dihydrochalcones in good yields accompanying 1-indanone derivatives in some cases, in the presence of anhydrous aluminum chloride. The scope, limitation, and mechanism of the tandem reaction were also explored. The intermolecular Friedel–Crafts alkylation for the ...