Reactions of carbonyl compounds with Grignard reagents in the presence of cerium chloride

T Imamoto, N Takiyama, K Nakamura…

文献索引：Imamoto, Tsuneo; Takiyama, Noboyuki; Nakamura, Kimikazu; Hatajima, Toshihiko; Kamiya, Yasuo Journal of the American Chemical Society, 1989 , vol. 111, # 12 p. 4392 - 4398

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被引用次数: 555

摘要

Abstract: The addition of Grignard reagents to ketones is significantly enhanced by cerium chloride with remarkable suppression of side reactions, particularly enolization. Some esters, which are prone to side reactions, also react readily with Grignard reagents in the presence of cerium chloride to give normal reaction products in reasonable to high yields.

~2%

606-86-0

1,3,3-三苯基-1-丙酮

~15%

~60%

~3%

~67%

~28%

~94%

~99%

~62%

~30%

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