Heterogeneous Pd/C??Catalyzed Ligand??Free, Room??Temperature Suzuki–Miyaura Coupling Reactions in Aqueous Media

T Maegawa, Y Kitamura, S Sako, T Udzu…

文献索引：Maegawa, Tomohiro; Kitamura, Yoshiaki; Sako, Satoko; Udzu, Takahiro; Sakurai, Ai; Tanaka, Asami; Kobayashi, Yusuke; Endo, Koichi; Bora, Utpal; Kurita, Takanori; Kozaki, Atsushi; Monguchi, Yasunari; Sajiki, Hironao Chemistry - A European Journal, 2007 , vol. 13, # 20 p. 5937 - 5943

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被引用次数: 169

摘要

Abstract A mild and efficient ligand-free Suzuki–Miyaura coupling reaction catalyzed by heterogeneous Pd/C was developed. Aryl bromides and triflates undergo the cross-coupling with aryl boronic acids in excellent yields without the presence of any additives in aqueous media at room temperature. Aryl vinyl boronic acids are also applicable to this coupling reaction and provide the trans-stilbene derivatives in high yields. The application of wet- ...