Simple Aza-Conjugate Addition Methodology for the Synthesis of Isoindole Nitrones and 3, 4-Dihydroisoquinoline Nitrones

LR Peacock, RSL Chapman, AC Sedgwick…

文献索引：Hatano, Bunpei; Sato, Haruna; Ito, Tomohiro; Ogata, Tateaki Synlett, 2007 , # 13 p. 2130 - 2132

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被引用次数: 5

摘要

... Further support for the intermediacy of 5 in the formation of nitrone 7a was obtained by treatment of aryl-aldehyde 12, with hydroxylamine under basic conditions which cleanly afforded the regioisomeric nitrone 13 (Scheme 2d). Indeed, carrying out the cyclization reaction of 1a ...