Synthesis and Characterization of 2, 5-Bis (2-pyridyl) thiophene

SA Al-Taweel

文献索引：Al-Taweel, Samir A. Phosphorus, Sulfur and Silicon and Related Elements, 2002 , vol. 177, # 5 p. 1041 - 1045

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被引用次数: 4

摘要

2-[2-(Trimethylsilyl) ethynyl] pyridine (6) was prepared in 95% yield by reaction of 2- bromopyridine with trimethylsilylacetylene in triethylamine in the presence of bis (triphenylphosphine) Palladium (II) chloride and Copper (I) iodide. Desilylation of (6) by refluxing with sodium hydroxide in methanol (yield 95%) of 2-ethynylpyridine (5). Oxidative coupling of (5) in pyridine by oxygen in the presence of Copper (I) chloride gives 70% ...