Efficient synthesis of 2-methyl-1-cyclopentene-1-carboxylic acid

…, KS Clement, JC Gilbert, B Wiechman

文献索引：Harding, Kenn E.; Clement, Katherine S.; Gilbert, John C.; Wiechman, Barry Journal of Organic Chemistry, 1984 , vol. 49, # 11 p. 2049 - 2050

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被引用次数: 39

摘要

The utility of 2-methyl-1-cyclopentene-1-carboxylic acid (1) as a synthetic intermediate in our research efforts' as well as the efforts of other research groups2 led us to develop a short, economical synthesis of this material. Previous synthe~ es~~~ proved unsuitable for routine preparation of 1 in large quantities. A synthetic approach involving organocuprate addition to derivatives of 2-carbomethoxycyclopentanone reported previously by one of and by ...