Topical mosquito repellents III: carboxamide acetals and ketals and related carbonyl addition derivatives

P Tsakotellis, HL Johnson, WA Skinner…

文献索引：Tsakotellis; Johnson; Skinner; Skidmore; Maibach Journal of pharmaceutical sciences, 1971 , vol. 60, # 1 p. 84 - 89

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被引用次数: 5

摘要

Abstract Slow release of topically applied mosquito repellents was attempted via formation of low volatility carbonyl addition derivatives of repellent alcohols and carbonyl compounds. Sufficiently rapid hydrolytic release of volatile, repellent moieties on the skin surface did not occur. Vapor repellency was due to the intact derivatives and was found to be dependent upon volatility characteristics. It was concluded that optimum volatility for prolonged topical ...