Organic letters

Two useful photolabile surfaces for solid-phase synthesis

TD Ryba, PG Harran

文献索引：Ryba, Troy D.; Harran, Patrick G. Organic Letters, 2000 , vol. 2, # 6 p. 851 - 853

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被引用次数: 11

摘要

o-Nitrobenzyl-based photolabile surfaces 3 and 4 have been synthesized from 2- phenylcyclohexanone and aminopropylsiloxane-grafted controlled pore glass. The procedures are simple and inexpensive and generate materials whose minimally functionalized reactive chromophore should tolerate a range of subsequent chemistries. Time-and solvent-dependent analysis of photodegradation demonstrates a performance ...