Synlett

The vinylogous mannich reaction: An efficient access to substituted nicotinonitriles

A Winter, N Risch

文献索引：Winter, Andreas; Risch, Nikolaus Synlett, 2003 , # 13 p. 1959 - 1964

全文：HTML全文

被引用次数: 5

摘要

Abstract A straightforward method for the preparation of substituted nicotinonitriles has been developed. Starting from conjugated β-enaminonitriles and iminium salts, this methodology establishes a convenient access to 6-aryl-(5), 6-amino-(16) and 6-carboxylic ester- substituted derivatives 14 and as well to acetic acid-substituted pyrroles 12.